Compile Data Set for Download or QSAR
maximum 50k data
Found 39 of ic50 data for polymerid = 5320,50002895
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM155523(US9011882, Table 1, Compound 18)
Affinity DataIC50:  3.30E+3nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50389868(CHEMBL2070857 | US9011882, Table 1, Compound 16)
Affinity DataIC50:  5.10E+3nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM155517(US9011882, Table 1, Compound 10)
Affinity DataIC50:  7.10E+3nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM155515(US9011882, Table 1, Compound 8)
Affinity DataIC50:  8.60E+3nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM155510(US9011882, Table 1, Compound 3)
Affinity DataIC50:  9.90E+3nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM34513(MLS000118887 | N-[2-(2,5-dimethoxyphenyl)ethyl]-2-...)
Affinity DataIC50:  9.90E+3nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM155521(US9011882, Table 1, Compound 14)
Affinity DataIC50:  1.05E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM155519(US9011882, Table 1, Compound 12)
Affinity DataIC50:  1.10E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM155522(US9011882, Table 1, Compound 17)
Affinity DataIC50:  1.18E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM155516(US9011882, Table 1, Compound 9)
Affinity DataIC50:  1.28E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50240715((S)-2-Amino-5-but-3-enimidoylamino-pentanoic acid ...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM155508(US9011882, Table 1, Compound 1)
Affinity DataIC50:  1.31E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM46658(1,2-benzothiazol-3-one | MLS-0254244.0001 | US9011...)
Affinity DataIC50:  1.32E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM155520(US9011882, Table 1, Compound 13)
Affinity DataIC50:  1.34E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM155514(US9011882, Table 1, Compound 7)
Affinity DataIC50:  1.37E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM155518(US9011882, Table 1, Compound 11)
Affinity DataIC50:  1.41E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM155512(US9011882, Table 1, Compound 5)
Affinity DataIC50:  1.77E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM155511(US9011882, Table 1, Compound 4)
Affinity DataIC50:  2.12E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Rattus norvegicus)
Christian-Albrechts-University Of Kiel

Curated by ChEMBL
LigandPNGBDBM50240959((S)-2-Amino-5-[N'-(2-methoxy-ethyl)-guanidino]-pen...)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of rat DDAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM155509(US9011882, Table 1, Compound 2)
Affinity DataIC50:  2.33E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM141899(US8921421, L-257 | hDDAH inhibitor, 2a)
Affinity DataKi:  1.30E+4nM IC50:  2.90E+4nMpH: 7.4Assay Description:This assay was used to determine the inhibiting effect of the inhibitors in a concentration of 1 mM. A standard incubation mixture consisted of 75 &#...More data for this Ligand-Target Pair
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50240959((S)-2-Amino-5-[N'-(2-methoxy-ethyl)-guanidino]-pen...)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM155524(US9011882, Table 1, Compound 19)
Affinity DataIC50:  3.99E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM155513(US9011882, Table 1, Compound 6)
Affinity DataIC50:  4.58E+4nMAssay Description:The L-citrulline assay was based upon an original test-tube method developed by Prescott and Jones in 1969 (Prescott, L. M. & Jones, M. E. Modified m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50070209(Aciphex | CHEBI:8768 | LY-307640 | Rabeprazole)
Affinity DataIC50:  5.30E+4nMAssay Description:Inhibition of human recombinant DDAH1 reduction in L-citrulline formation using ADMA as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50254452(CHEMBL197234 | N-omega-propargyl-L-arginine)
Affinity DataIC50:  5.50E+4nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM141900(US8921421, 3)
Affinity DataKi:  1.80E+4nM IC50:  7.00E+4nMpH: 7.4Assay Description:This assay was used to determine the inhibiting effect of the inhibitors in a concentration of 1 mM. A standard incubation mixture consisted of 75 &#...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50255074((S)-2-Amino-5-butyrimidoylamino-pentanoic acid | C...)
Affinity DataIC50:  7.00E+4nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50254449(CHEMBL456882 | N5-(1-iminopent-3-enyl)-L-ornithine)
Affinity DataIC50:  7.90E+4nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50254451(CHEMBL106423 | N-omega-(but-3-enyl)-L-arginine)
Affinity DataIC50:  1.89E+5nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50240714((2S)-5-{[(allylamino)(iminio)methyl]amino}-2-ammon...)
Affinity DataIC50:  2.07E+5nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50240716((S)-2-Amino-5-(N'-propyl-guanidino)-pentanoic acid...)
Affinity DataIC50:  2.83E+5nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50254450((S)-2-Amino-5-propionimidoylamino-pentanoic acid |...)
Affinity DataIC50:  3.00E+5nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50242405((2S)-2-amino-4-sulfanylbutanoic acid | CHEMBL46966...)
Affinity DataIC50:  6.40E+5nMAssay Description:Inhibition of human recombinant DDAH1More data for this Ligand-Target Pair
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50404858(CHEMBL351569)
Affinity DataIC50:  1.40E+6nMAssay Description:Inhibition of human recombinant His6-tagged DDAH1 expressed in Escherichia coli BL21(DE3) using Nomega,Nomega-dimethyl-L-arginine as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50421231(CHEMBL2087646)
Affinity DataIC50:  2.70E+6nMAssay Description:Inhibition of human recombinant His6-tagged DDAH1 expressed in Escherichia coli BL21(DE3) using Nomega,Nomega-dimethyl-L-arginine as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50375814(CHEMBL260628)
Affinity DataIC50: >5.00E+6nMAssay Description:Inhibition of human recombinant DDAH1 expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50049254((2S)-2-amino-5-(N-methylcarbamimidamido)pentanoic ...)
Affinity DataIC50: >5.00E+6nMAssay Description:Inhibition of human recombinant DDAH1 expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM50375815(CHEMBL408088)
Affinity DataIC50: >5.00E+6nMAssay Description:Inhibition of human recombinant DDAH1 expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed